Insights on alpha-lipoic acid

Where to buy alpha-lipoic acid in India?

Alpha-lipoic acid, the common food supplement, can be purchased from any drug store in India. The bulk quantity of the chemical is available for purchase from a wholesale chemical supplier or a third-party dealer. The trend of bulk chemical purchase directly from the manufacturer, supplier, or the third-party dealer is popular in India. But the trend is slowly moving towards digitization, which makes the entire chemical supply process easy and efficient. While talking about the digitization in the chemical industry, the name Carbanio cannot be neglected. Being India’s largest B2B chemical platform, Carbanio has managed to popularize the concept of digitization in the Indian chemical industry. If you are looking to buy alpha-lipoic acid or any other chemical, look no further. Carbanio offers chemicals at great deals and gets it delivered to your doorstep within the estimated time.

The on-going coronavirus breakout and the regional lockdown has also played an important role in digitizing the chemical industry. The transport restrictions, social distancing norms, and the fear of the rapidly spreading virus, had made the scenario difficult for buyers. That’s when the digital platforms like Carbanio.com came for the rescue. Carbanio even sourced chemicals to the reputed institutions during the lockdown, who were in urgent need of chemicals for creating the COVID-19 vaccine.

What is alpha-lipoic acid?

Alpha-lipoic acid is a compound that is naturally made in the body to serve vital functions at the cellular level by breaking down carbohydrates and produce energy for other organs in the body. It has powerful antioxidant properties and is linked with many benefits like lowering the sugar level, slow down skin ageing process, and reduce inflammation to name a few. Though alpha lipoic acid is an important compound for vital body functions, it is produced in a smaller amount. That’s why people depend on intake of certain food or supplements to improve the amount of alpha-lipoic acid in the body.

Chemical formulaC8H14O2S2
IUPAC name(R)-5-(1,2-Dithiolan-3-yl) pentanoic acid
Molar mass206.32 g·mol−1
AppearanceYellow needle-like crystals
Melting point60 – 62° C
SolubilitySoluble in ethanol, slightly soluble in water

Alpha-lipoic acid foods

Alpha-lipoic acid is available in a certain food but in lower quantity. They include:

  • Red meat
  • Spinach
  • Tomatoes
  • Broccoli
  • Carrots
  • Beets
  • Yams
  • Rice bran
  • Yeast
  • Potatoes
  • Brussels sprouts

What is alpha-lipoic acid used for?

  • The oral or intravenous (IV) dose of alpha-lipoic acid is found to improve blood sugar levels in people with type 2 diabetes.
  • Alpha-lipoic acid is an antioxidant. An antioxidant protects against damage to the body’s cells.
  • Oral or IV of 600-1800 mg alpha-lipoic acid improves symptoms of burning sensation, pain, and numbness in the legs and arms of diabetic patients.
  • Intake of alpha-lipoic acid for 16 weeks lowers the total cholesterol level and low-density lipoprotein in people with or without hyperlipidemia.
  • Alpha-lipoic acid is used in the weight reduction process. Some research claim that taking alpha-lipoic acid for 8-48 weeks can slightly reduce weight in adults.
  • Some researchers claim that applying facial creams with 5% alpha-lipoic acid can reduce fine lines and skin roughness, but there is not enough evidence to prove the anti-ageing properties of alpha-lipoic acid.
  • Alpha-lipoic acid is used to treat inflammation. It significantly reduces the C-reactive proteins, the inflammation maker.
  • Alpha-lipoic acid skin care products are popular and claim to reduce fine lines, diminish large pores, and gives skin a healthy glow.
  • Alpha-lipoic acid neuropathy supplements claim to help with nerve damage caused by diabetes or cancer treatments.

You can now buy alpha-lipoic acid online at Carbanio.com and experience hassle-free chemical purchase. Visit our website today and get great deals on any chemical you would want to buy.

Side effects of alpha-lipoic acid

Alpha-lipoic acid is generally safe with minimal or no side effects when taken up to 2,400 mg. However mild side effects are seen in rare cases:

  • Common side effects include nausea and skin rashes
  • There can be signs of an allergic reaction such as swelling of face, lips, throat, or tongue
  • It can sometimes lower blood sugar causing headache, sweating, dizziness, weakness, fast heart rate, or feeling jittery
  • Mild headache or a feeling like you might pass out

When taken orally by pregnant women, it is possibly safe up to 600mg per day for about 4 weeks. It can be taken from 10th week of pregnancy and can be continued up to 37th week. There is not much relevant information regarding the use of alpha-lipoic acid in case of breastfeeding mothers. It is safe to avoid the usage or consult your doctor before use.

Safe dosage of alpha-lipoic acid

Alpha-lipoic acid is completely safe to take orally or intravenously in the right dosage. Here is the safe dose you can use:

In adults

Oral dose

Diabetic patients and people with symptoms of nerve pain with diabetes: 300-1800 mg per day.

High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia): 300-1200 mg per day for up to 16 weeks.

Obesity: 1800 mg per day to be taken for 20 weeks.

Intravenous:

Diabetic patients and people with symptoms of nerve pain with diabetes: 500-1200 mg per day.

In children

Diabetes: 300 mg of alpha-lipoic acid in combination with insulin should be taken twice a day.

Alpha-lipoic acid as weight loss supplement

Alpha-lipoic acid is gaining popularity for its antioxidant properties and use in diabetes treatment. Now, researches have shown that this noble compound may affect weight loss too. Studies on animals reveal that alpha-lipoic acid reduces the activity of enzymes called AMP-activated protein kinase (AMPK), which is active when you are hungry. Suppressing AMPK activity will control the hunger and eventually burn calories. Hence, it has been proved to burn calories in animals.

In human beings, alpha-lipoic acid is found to impact weight loss. In a recent analysis, researchers found out that people who took the alpha-lipoic acid supplement lost an average of 0.7 kgs more than people taking a placebo over an average of 14 weeks. Another analysis revealed that over 23 weeks, the people who took alpha-lipoic acid lost over 1.27 kg than the ones with a placebo.

The studies reveal that alpha-lipoic acid has an impact of weight loss in human beings, but to lower levels. Drastic weight loss cannot be achieved by consuming alpha-lipoic acid supplements alone.

Alpha-lipoic acid and diabetes

Diabetes is a major health problem faced by nearly 400 million adults across the globe. If left untreated, it can cause heart disease and kidney failure. Alpha-lipoic acid is popularly used for the treatment of diabetes as it has evidence supporting its properties of lowering blood sugar levels. A recent report claims that alpha-lipoic acid may reduce insulin resistance and lower fasting blood sugar levels.

Researchers say that alpha-lipoic acid removes the fat accumulation in muscle cells, which makes insulin less effective, thereby lowering the blood sugar level. This helps in reducing the risk of diabetes complications. Though evidence is in support of alpha-lipoic acid being a potential drug to control blood sugar levels, it cannot be considered as a complete treatment. It is always advisable to consult the doctor and continue the medication as prescribed.

Alpha-lipoic acid: Global Market

The increasing growth of alpha-lipoic acid in food and pharmaceutical industry has led to the increasing growth of its market size. The growing demand of alpha-lipoic acid for use in medicines, weight loss products, and dietary supplements have led to the increase in production which is expected to reach $19 million by 2024. The current market size is about $11 million, which is expected to grow at CAGR of 6% to reach the estimated $19 million by 2024.

The growing number of diabetic patients in the Asia Pacific countries including India, China, and Malaysia has subsequently increased the market for alpha-lipoic acid for use in the production of drugs for diabetic treatment. The market size in the Asia Pacific region was estimated at $3.5 million in 2016, which is expected to grow at CAGR of 6% by 2024. The growing healthcare and pharmaceutical industry in North America have led to an increase in the market size in the region, which will not slow down anytime soon.

Key Players of global alpha-lipoic acid market

The major manufacturers and suppliers operating in the global alpha lipoic acid market are:

  • Jarrow Formulas, Inc.
  • NOW Health Group, Inc.
  • Swanson Health Products, Inc.
  • Pharmavite LLC
  • Rexall Sundown, Inc.
  • Solgar Inc.
  • Spring Valley Laboratories, Inc.
  • Nature’s Bounty, Inc.
  • GNC Holdings Inc.

With numerous benefits of alpha-lipoic acid in the food and pharmaceutical industry, the demand and supply chain will not be affected anytime soon. As estimated, the market size will increase by 2024 and beyond.