What is Nicotine Sulphate used for?

What is Nicotine Sulphate?

Nicotine sulphate is a chemical compound which forms the most important intermediate product in the production of nicotine; it is formed from neutralization of nicotine with sulfuric acid. It emits toxic fumes of carbon monoxide and oxides of nitrogen, upon heating; hence, it is classified as an extremely toxic chemical. The oral lethal dose in humans is estimated to be less than 5 mg/kg for a 70 kg individual. Death is possible by ingestion, inhalation, or even extreme absorption by the skin. The respiratory failure can cause paralysis of the respiratory muscles, while other symptoms include central nervous stimulation.

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Chemical Composition of Nicotine Sulphate

Nicotine sulphate is a chemical compound with the formula C10H14N2 · H2SO4. It appears as a clear, colorless solution in the liquid state, while solid appears as white solid. It produces toxic oxides of nitrogen during combustion; and produces sulfate salt of nicotine that is an alkaloid obtained from tobacco, which have many health impacts associated with it. It is found to be toxic by ingestion, inhaled, or contact with skin.

Properties of nicotine sulphate include:

AppearanceWhite crystalline solid, clear liquid
Molecular Weight422.5
Density1.15 AT 20 °C
Melting pointDecomposes on heating 
SolubilitySoluble in water and alcohol

Uses of Nicotine Sulphate

Nicotine sulphate is used in:

  • Nicotine sulphate 40% is popularly used as a pesticide and insecticide
  • Nicotine sulphate 40% is a bio-degradable alternative to synthetic chemicals to kill remnants on fruits and vegetables
  • It is used in production of nicotine, a recreational drug.
  • It is used as pharmaceutical intermediate
  • It is used as pesticide intermediate
  • It can be used to produce nicotine phosphate
  • It is used in the production of nicotine citrate
  • It plays key role in production of nicotine salts 

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How safe is Nicotine Sulphate?

40% aqueous solution of nicotine sulphate is commonly used for industrial and laboratory applications. It has a certain amount of health impacts associated with it. 

The potential health risks include:

Eyes: On contact with eyes, nicotine sulphate causes eye irritation.

Skin: On superficial contact with the skin, it causes skin irritation. It is found to have the potential to be absorbed by the skin, when absorbed by the skin, it can be fatal.

Ingestion: When swallowed, nicotine sulphate can cause irritation of the respiratory tract. It can also be fatal depending on the scenario.

Inhalation: It is harmful when inhaled. It causes respiratory tract irritation, and may also cause lung damage in extreme cases.

Chronic: Chronic effects include lung damage; it also found to have adverse reproductive effects in animal studies. 

Others: It is found to cause central nervous system stimulation in some cases.

First aid measures:

Eyes: When nicotine sulphate comes in contact with eyes, flush eyes with plenty of cold water for at least 15 minutes; then get medical help.

Skin: On skin exposure it is advised to get immediate medical help. Before that, remove the contaminated clothing and flush the affected with plenty of cold water for at least 15 minutes.

Ingestion: In the event of ingestion, get medical help without any delay. Do not induce vomiting.

Inhalation: When inhaled, expose the person to fresh air immediately. 

Top Manufacturers of Nicotine Sulphate

Nicotine sulphate 40% is the most produced among its other purity ranges. It’s global demand and supply is due to its increasing use as pharmaceutical and pesticide intermediate. the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region includes countries in the US and Canada; Europe covers France, Spain, UK, Germany, Italy, Russia, and Rest of Europe. Asia Pacific further covers India, China, Japan, South Korea, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA. 

  • Jiatian Biotech
  • He Nuo Biotech
  • BGP Group
  • Tianze Biological
  • Guanghua Bio

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